Hi, I am trying to run sopa Baysor cell segmentation pipeline with 10x xenium data. I am using snakemake version 9.14.0, and sopa newest version. When i run ...
Spatial transcriptomics provides a unique perspective on the genes that cells express and where those cells are located. However, the rapid growth of the technology has come at the cost of ...
Transcriptomics represents a critical discipline in cancer research, enabling comprehensive mapping of gene expression profiles and the identification of fusion genes implicated in tumor development.
The liver is remarkable for its ability to regenerate after injury, yet when this process fails, acute liver failure (ALF) carries devastating outcomes. Traditional research methods, reliant on bulk ...
Spatial transcriptomics enables researchers to measure gene expression in tissue sections while preserving their spatial organisation. Unlike traditional RNA sequencing, which requires dissociating ...
Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, public reviews, and a provisional response from the authors. In the manuscript, ...
As life sciences enter the era of precision biology, spatial genomics and transcriptomics are transforming our ability to decode gene expression not just at the molecular level, but also within the ...
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A classifier to assess section integrity. (A) Generation of the transcript mask. The transcript density image was converted to a binary mask using a random forest classifier. (B) Generation of the ...
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